A Locally Advanced Endometrioid Adenocarcinoma Arising from Vaginal Endometriosis: Management and Review of the Literature

Endometrioid adenocarcinoma associated with endometriosis at extrauterine or extraovarian localization is a rare entity. Often presenting local spread without nodal and distant metastasis, this entity has no specific staging system nor treatment guidelines. In the case of spread, decision requires personalization. article, we present diagnosis surgical systemic 56-year-old woman diagnosed an endometriosis-associated advanced endometrioid vagina involvement. Following extensive review scarce data reported to guide choices in setting, proposed multidisciplinary laparoscopic cytoreduction, four cycles adjuvant chemotherapy carboplatin paclitaxel, radiotherapy brachytherapy. Due anaphylactic reaction on first administration, paclitaxel was replaced nab-paclitaxel. Despite many negative prognostic factors, patient free from relapse after 48 months. We report locally vagina, pelvic relevant literature similar cases.